Technical Skills

Driven by my deep interest and solid foundation in organic chemistry, I continuously seek opportunities to learn and refine my skills. 

Organic synthesis typically involves three crucial stages: 

Preparation, Purification, and Characterization.

Here, I will showcase 

• Reactions I have independently performed.
• Purification techniques and instruments I've utilized in the laboratory.
• My proficiency with characterization tools through my research experience.

1. Preparation (synthesis):

1. Synthesis of aromatic core: Pyrrolo-acridine derivatives, xanthene, phthalazine
2. Modification of aromatic core: methylene to carbonyl, nitrile to primary amine
3. Synthesis of starting materials: Isatin and its derivatives, 5-phenylcyclohexane-1,3-dione
4. Commonly known reactions: esterification, reduction, nitration, alkylation, and so on.
5. Complexation:

2. Purification:

1. Column chromatography: Purification of pyrrolo-acridine derivatives
2. PTLC: Some cases of pyrrolo-acridine synthesis
3. TLC: To monitor progress and completion of reaction
4. Distillation: Solvent distillation (ethanol, acetone, n-hexane, ethyl acetate, and so on)
5. Solvent extraction: Preparation of isatin By the Sandmeyer method
6. Rotary evaporation at a reduced pressure: Remove excess solvent from the reaction mixture.
7. Recrystallization: Used to get pure product for NMR/HMRS/single crystal

3. Characterization (Operational Command):

1. Single crystal XRD: (Prepared single crystal and analyzed data.)
2. NMR Proton and Carbon-13: (Prepared NMR-grade samples and analyzed NMR data.)
3. HRMS: (Prepared HRMS-grade samples and investigated masses and molecular formula)
4. FT-IR: (Operated FTIR and analyzed FTIR data.)
5. UV: (Operated Shimadzu UV-1900i Spectrophotometer and analyzed data.)